Cancer Treatment Centers in South Carolina

After a Cancer Diagnosis in South Carolina: How to Use This Resource

A cancer diagnosis can be overwhelming for patients and caregivers. Many people experience fear, confusion, and uncertainty while trying to understand what comes next. In South Carolina, where communities range from large cities to small rural towns, knowing where cancer treatment centers are located can help reduce stress and support better planning.

This page on South Carolina cancer treatment centers was created to help patients and caregivers understand the range of cancer care options available across the state and nearby regions. It is an educational resource only. It does not provide medical advice, recommend treatments, or suggest that one provider is better than another. Instead, it organizes information to support informed conversations with qualified healthcare professionals.

What This List Is – and What It Is Not

This list is an educational navigation tool that highlights cancer treatment centers serving South Carolina residents. It is not a ranking, endorsement, or recommendation of any hospital, clinic, or cancer program. Inclusion on this page does not mean that a center is the right choice for every patient.

Cancer care decisions are personal and depend on many factors, including diagnosis, insurance coverage, transportation, work schedules, income, and caregiver support. This guide is designed to help patients and caregivers see what types of cancer treatment centers exist so they can ask informed questions and explore next steps with greater confidence.

How Cancer Care Access Works in South Carolina

South Carolina has several population centers, including Charleston, Columbia, Greenville, and Spartanburg, where many healthcare services are located. Patients living near these areas may have easier access to hospitals and specialty programs. However, people in rural or coastal communities may need to travel longer distances for certain types of cancer care.

Transportation, time away from work, and caregiving responsibilities can affect access to treatment. Some patients receive most of their care locally, while others travel within South Carolina or to nearby states for specialized services or second opinions. Understanding where cancer treatment centers are located can help patients and caregivers plan ahead.

Looking for Additional Providers?

This guide uses a hybrid approach that combines a curated list of cancer treatment centers with links to trusted directories. Because healthcare programs and services can change over time, not every cancer care provider serving South Carolina residents may appear on this page.

If you do not see a cancer treatment center near you, the directory links included later in this resource can help you explore additional options across South Carolina and nearby states.

Tier 1 – NCI-Designated Cancer Centers

Hollings Cancer Center at the Medical University of South Carolina (Charleston)

Address: 86 Jonathan Lucas St, Charleston, SC 29425

Phone: (843) 792-0000

Website: https://hollingscancercenter.musc.edu

Tier 2 – Major Academic & Health-System Cancer Centers

Prisma Health Cancer Institute (Greenville)

Address: 900 W Faris Rd, Greenville, SC 29605

Phone: (864) 455-4600

Website: https://prismahealth.org/services/cancer

Prisma Health Cancer Institute (Columbia)

Address: 1301 Taylor St, Columbia, SC 29201

Phone: (800) 523-9433

Website: https://prismahealth.org/services/cancer

McLeod Cancer & Blood Center (Florence)

Address: 555 E Cheves St, Florence, SC 29506

Phone: (843) 777-2000

Website: https://www.mcleodhealth.org/services/cancer/

Roper St. Francis Cancer Care (Charleston)

Address: 2085 Henry Tecklenburg Dr, Charleston, SC 29414

Phone: (843) 402-2222

Website: https://www.rsfh.com/services/cancer-care/

Tier 3 – Community & Regional Cancer Centers

AnMed Cancer Center (Anderson)

Address: 800 N Fant St, Anderson, SC 29621

Phone: (864) 716-4400

Website: https://anmed.org/services/cancer-care

Spartanburg Regional Gibbs Cancer Center (Spartanburg)

Address: 101 E Wood St, Spartanburg, SC 29303

Phone: (864) 560-4000

Website: https://www.spartanburgregional.com/services/cancer

Lexington Medical Center Cancer Care Services (West Columbia)

Address: 2720 Sunset Blvd, West Columbia, SC 29169

Phone: (803) 321-9000

Website: https://lexmed.com/services/cancer-care

Grand Strand Medical Center Cancer Program (Myrtle Beach)

Address: 809 82nd Pkwy, Myrtle Beach, SC 29572

Phone: (843) 692-3000

Website: https://grandstrandmed.com/specialties/cancer-care

Self Regional Healthcare Cancer Center (Greenwood)

Address: 1325 Spring St, Greenwood, SC 29646

Phone: (864) 225-4000

Website: https://www.selfregional.org/services/cancer-care

Tier 4 – Community Oncology Groups & Networks

Carolina Blood and Cancer Care Associates (Multiple Locations)

Address: 1330 Boeing Blvd, North Charleston, SC 29418

Phone: (843) 722-4000

Website: https://www.cbcca.com/locations

Lowcountry Hematology & Oncology (Multiple Locations)

Address: 2093 Henry Tecklenburg Dr, Charleston, SC 29414

Phone: (843) 402-2200

Website: https://www.lowcountryhematologyoncology.com/locations

Tier 5 – Pediatric & Specialty Cancer Centers

MUSC Shawn Jenkins Children’s Hospital — Pediatric Hematology & Oncology (Charleston)

Address: 10 McClennan Banks Dr, Charleston, SC 29425

Phone: (843) 792-0000

Website: https://musckids.org/our-services/cancer

Prisma Health Children’s Hospital — Pediatric Oncology (Columbia)

Address: 7 Richland Medical Park Dr, Columbia, SC 29203

Phone: (800) 523-9433

Website: https://prismahealth.org/services/childrens/pediatric-cancer

Hollings Cancer Center — Bone Marrow Transplant Program (Charleston)

Address: 86 Jonathan Lucas St, Charleston, SC 29425

Phone: (843) 792-0000

Website: https://hollingscancercenter.musc.edu/patient-care/blood-and-marrow-transplant

Tier 6 – Nearby Out-of-State Centers of Excellence

Winship Cancer Institute of Emory University (Atlanta, GA)

Address: 1365 Clifton Rd, Atlanta, GA 30322

Phone: (404) 778-4000

Website: https://winshipcancer.emory.edu

Duke Cancer Institute (Durham, NC)

Address: 40 Duke Medicine Cir, Durham, NC 27710

Phone: (919) 684-5000

Website: https://www.dukecancerinstitute.org

UNC Lineberger Comprehensive Cancer Center (Chapel Hill, NC)

Address: 101 Manning Dr, Chapel Hill, NC 27514

Phone: (919) 966-2644

Website: https://unclineberger.org

Looking for Additional Cancer Care Providers?

The cancer treatment centers listed on this page are curated and organized into tiers to help patients and caregivers better understand the types of cancer care available to South Carolina residents. This list is not intended to be exhaustive, and some legitimate cancer care providers or programs may not appear here.

If you do not see a cancer treatment center near you, the trusted directories below can help you explore additional cancer care options across South Carolina and in nearby states.

• 
  National Cancer Institute — Find a Cancer Center
  
• American College of Surgeons — CoC Program Finder
• 
  VA Facility Locator
  

Can’t find a cancer treatment center near you? Patients and caregivers may contact cancereducationfoundation.local for guidance in locating additional cancer care resources.

Important Note

This list is provided for educational and informational purposes only. It is intended to help patients and caregivers understand the range of cancer treatment options available and is not a recommendation or endorsement of any specific provider.

While we strive to present a broad and representative overview of cancer treatment centers, this list may not include every cancer care provider or program in the state, and services offered can vary by location.

Patients are encouraged to discuss care options with qualified healthcare professionals and to contact treatment centers directly to confirm services, availability, and suitability for their individual needs.

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Disclaimer: This information is for educational purposes only and is not medical advice. Talk to a healthcare provider about questions related to your health.