Cancer Treatment Centers in Pennsylvania

After a Cancer Diagnosis in Pennsylvania: How to Use This Resource

A cancer diagnosis can change life quickly for patients and caregivers. Many people feel overwhelmed as they try to understand medical terms, schedule appointments, and manage daily responsibilities. In Pennsylvania, where communities range from large cities to small rural towns, knowing where cancer treatment centers are located can help reduce stress and support clearer planning.

This page on Pennsylvania cancer treatment centers was created to help patients and caregivers understand the range of cancer care options available across the state. It is an educational resource only. It does not provide medical advice, recommend treatments, or suggest that one provider is better than another. Instead, it organizes information to support informed discussions with qualified healthcare professionals.

How to Use the List Below

The cancer treatment centers in Pennsylvania are organized into tiers to make the information easier to understand. These tiers describe different care settings and organizational structures, not levels of quality. Some patients begin care locally and later seek referrals or second opinions for specialized services.

Balancing travel distance, available services, insurance considerations, and caregiver support is an important part of decision-making. It is common for patients to work with more than one cancer care provider during treatment and follow-up.

Looking for Additional Providers?

This guide uses a hybrid approach that combines a curated list of cancer treatment centers with links to trusted directories. Because healthcare programs and services can change over time, not every cancer care provider serving Pennsylvania residents may appear on this page.

If you do not see a cancer treatment center near you, the directory links included later in this resource can help you explore additional options across Pennsylvania and nearby states.

A Reassuring Closing

Facing cancer can feel overwhelming, especially when access to care or travel is a concern. Across Pennsylvania and the surrounding region, healthcare professionals and organizations work to support patients and families with compassion, dignity, and respect. Learning about cancer treatment centers in Pennsylvania is one step toward feeling more informed and prepared. This resource is here to support calm decision-making and thoughtful conversations as you move forward.

Tier 1 – NCI-Designated Cancer Centers

University of Pennsylvania Abramson Cancer Center (Philadelphia)

Address: 3400 Civic Center Blvd, Philadelphia, PA 19104

Phone: (800) 789-3662

Website: https://www.pennmedicine.org/cancer

UPMC Hillman Cancer Center (Pittsburgh)

Address: 5150 Centre Ave, Pittsburgh, PA 15232

Phone: (412) 647-4000

Website: https://hillman.upmc.com

Fox Chase Cancer Center (Philadelphia)

Address: 333 Cottman Ave, Philadelphia, PA 19111

Phone: (888) 369-7339

Website: https://www.foxchase.org

Tier 2 – Major Academic & Health-System Cancer Centers

Thomas Jefferson University Sidney Kimmel Cancer Center (Philadelphia)

Address: 233 S 10th St, Philadelphia, PA 19107

Phone: (800) 533-4633

Website: https://www.jeffersonhealth.org/clinical-specialties/cancer

Penn State Cancer Institute (Hershey)

Address: 500 University Dr, Hershey, PA 17033

Phone: (717) 531-0000

Website: https://cancer.psu.edu

Allegheny Health Network Cancer Institute (Pittsburgh)

Address: 4800 Friendship Ave, Pittsburgh, PA 15224

Phone: (412) 359-4000

Website: https://www.ahn.org/services/cancer

Geisinger Cancer Institute (Danville)

Address: 100 N Academy Ave, Danville, PA 17822

Phone: (800) 275-1236

Website: https://www.geisinger.org/patient-care/conditions-treatments-specialty/cancer-care

Tier 3 – Community & Regional Cancer Centers

Lehigh Valley Topper Cancer Institute (Allentown)

Address: 1240 S Cedar Crest Blvd, Allentown, PA 18103

Phone: (888) 402-7000

Website: https://www.lvhn.org/treatment-options/cancer

Main Line Health Cancer Care (Bryn Mawr)

Address: 130 S Bryn Mawr Ave, Bryn Mawr, PA 19010

Phone: (484) 565-0000

Website: https://www.mainlinehealth.org/specialties/cancer-care

Lancaster General Health Ann B. Barshinger Cancer Institute (Lancaster)

Address: 2102 Harrisburg Pike, Lancaster, PA 17601

Phone: (717) 544-0000

Website: https://www.lancastergeneralhealth.org/services-and-treatments/cancer-care

Reading Hospital McGlinn Cancer Institute (Reading)

Address: 420 S 5th Ave, West Reading, PA 19611

Phone: (610) 988-3000

Website: https://towerhealth.org/services/cancer-care

WellSpan Cancer Center (York)

Address: 1001 S George St, York, PA 17403

Phone: (717) 851-0000

Website: https://www.wellspan.org/services/cancer-care

Tier 4 – Community Oncology Groups & Networks

Alliance Cancer Specialists (Multiple Locations)

Address: 1240 S Cedar Crest Blvd, Allentown, PA 18103

Phone: (484) 375-0000

Website: https://alliancecancer.com/locations/

Hematology Oncology Associates of Central Pennsylvania (Multiple Locations)

Address: 120 S Spotswood Dr, Camp Hill, PA 17011

Phone: (717) 761-6000

Website: https://www.hoacpa.com/locations

Tier 5 – Pediatric & Specialty Cancer Centers

Children’s Hospital of Philadelphia (CHOP) — Pediatric Oncology (Philadelphia)

Address: 3401 Civic Center Blvd, Philadelphia, PA 19104

Phone: (215) 590-6000

Website: https://www.chop.edu/centers-programs/cancer-center

UPMC Children’s Hospital of Pittsburgh — Pediatric Hematology & Oncology (Pittsburgh)

Address: 4401 Penn Ave, Pittsburgh, PA 15224

Phone: (412) 692-5000

Website: https://www.chp.edu/our-services/cancer

Penn Medicine Blood & Marrow Transplant Program (Philadelphia)

Address: 3400 Civic Center Blvd, Philadelphia, PA 19104

Phone: (800) 789-3662

Website: https://www.pennmedicine.org/cancer/programs/blood-and-marrow-transplant

UPMC Hillman Cancer Center — Bone Marrow Transplant Program (Pittsburgh)

Address: 5150 Centre Ave, Pittsburgh, PA 15232

Phone: (412) 647-4000

Website: https://hillman.upmc.com/patients/services/bone-marrow-transplant

Tier 6 – Nearby Out-of-State Centers of Excellence

Memorial Sloan Kettering Cancer Center (New York, NY)

Address: 1275 York Ave, New York, NY 10065

Phone: (212) 639-4000

Website: https://www.mskcc.org

Johns Hopkins Sidney Kimmel Comprehensive Cancer Center (Baltimore, MD)

Address: 401 N Broadway, Baltimore, MD 21287

Phone: (410) 955-5000

Website: https://www.hopkinsmedicine.org/kimmel-cancer-center

Cleveland Clinic Taussig Cancer Institute (Cleveland, OH)

Address: 9500 Euclid Ave, Cleveland, OH 44195

Phone: (216) 444-5000

Website: https://my.clevelandclinic.org/departments/cancer

Looking for Additional Cancer Care Providers?

The cancer treatment centers listed on this page are curated and organized into tiers to help patients and caregivers better understand the types of cancer care available to Pennsylvania residents. This list is not intended to be exhaustive, and some legitimate cancer care providers or programs may not appear here.

If you do not see a cancer treatment center near you, the trusted directories below can help you explore additional cancer care options across Pennsylvania and in nearby states.

• 
  National Cancer Institute — Find a Cancer Center
  
• American College of Surgeons — CoC Program Finder
• 
  VA Facility Locator
  

Can’t find a cancer treatment center near you? Patients and caregivers may contact cancereducationfoundation.local for guidance in locating additional cancer care resources.

Important Note

This list is provided for educational and informational purposes only. It is intended to help patients and caregivers understand the range of cancer treatment options available and is not a recommendation or endorsement of any specific provider.

While we strive to present a broad and representative overview of cancer treatment centers, this list may not include every cancer care provider or program in the state, and services offered can vary by location.

Patients are encouraged to discuss care options with qualified healthcare professionals and to contact treatment centers directly to confirm services, availability, and suitability for their individual needs.

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Disclaimer: This information is for educational purposes only and is not medical advice. Talk to a healthcare provider about questions related to your health.